PDA 374 Technical Report No. 22: Process Simulation for Aseptically Filled Products

12 Sep 2024
Washington, DC

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The objective of aseptic processing is to prevent the microbiological contamination of sterile product manufactured using the process. The verification of the ability of the process to produce sterile product is evaluated by aseptic process simulation studies or media fills.

This training course is based on PDA Technical Report No. 22: Process Simulations for Aseptically Filled Products, as well as relevant topics from PDA Points to Consider for Aseptic Processing: Part 2, and the EMA draft Annex 1 revision. The training course will address various elements required in the design and execution of aseptic process simulations to include personnel qualification, media selection and preparation, filling considerations, interventions, duration, and number of units filled, pre and post incubation inspections, incubation conditions, acceptance criteria and investigations and corrective actions. The use of risk-based decision making will be considered.

Participants will also receive a free copy of PDA Technical Report No. 22: Process Simulation for Aseptically Filled Products.

Upon completion of this training course, the attendee will be able to:

  1. Identify the updated scientific and regulatory technology and expectations in the design, operation, and interpretation of process simulations
  2. Discuss process simulation concepts and principles such as the number and frequency of simulations, worst case and risk assessment, and ongoing evaluations
  3. Describe how to use risk management as it applies to aseptic processing simulations
  4. Discuss how process simulations can be applied to various types of aseptically processed products (lyophilized products and powders)
  5. Explain why environmental monitoring is an important element of process simulations
  6. Discuss the necessary documentation associated with process simulations
  7. Apply modern concepts to establish appropriate acceptance criteria for aseptic process simulations, evaluate the results and as necessary investigate any failures and recommend appropriate corrective and preventive actions

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By Air The Westin Washington, DC Downtown is accessible from three major airports: Ronald Reagan Washington National Airport (DCA - approx. 5 miles/8 km), the Washington Dulles International Airport (IAD - approx. 28 miles/45 km), and the Baltimore/Washington International Thurgood Marshall Airport (BWI - approx. 34 miles/55 km).
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$999

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$699

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$1,199

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CANCELLATION: If a cancellation request is received 30 days before the event, a credit (registration fee paid minus a 200.00 USD/EUR processing fee) will be given. No credits will be given for cancellation requests received less than 30 days before the event. Cancellation requests must be emailed to registration@pda.org.

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Elevate your brand and maximize your exposure by becoming a sponsor at the PDA 374 Technical Report No. 22: Process Simulation for Aseptically Filled Products! Connect with industry leaders, showcase your products and services, and establish your company as a key player in the field.

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