Glossary Terms (Simple List)
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Superheated Water
Water in a liquid phase at a tempe- rature above 100°C requiring overpressure to maintain this state. (TR01)
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Superheated Water Process
A sterilization process in which the heating medium is superheated water that is continuously circulated with air overpressure. This process requires air overpressure to keep the water in a liquid state. [Synonyms: water cascade, water spray process, water immersion process, water submersion process, raining water process, steam-air-water process] (TR01)
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Superiority
A comparison with the primary objective of showing that the result from one method is superior to the method being compared. This is usually demonstrated by showing that the true difference is likely to lie between zero and the upper equivalence margin. (TR57)
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Supplemental Testing or Inspection
Destructive reconstitution, dilution, transfer, clearing, solubilizing, filtration, screening, or sieving that allows a product to be visually examined or evaluated microscopically to determine the presence, type, and size of foreign particulate contamination present within the product, container, or device. (TR79)
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Supplier
The entity with whom the agreement of the quality level is made and the transaction of purchase is made; the last link in the chain of manufacturers and distributors. The supplier may be the manufacturer.(TR76)
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Supply Chain
The process by which a drug product is shipped and distributed from the manufacturer to the end user. (TR39)
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Surface Tension
The tendency of the surface of a liquid to contract to the smallest area possible under defined conditions. It is expressed as dynes per centimeter. (TR26)
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Surfactant
A soluble compound that reduces the surface tension of a liquid or reduces interfacial tension between two liquids (causing formation or micelles) or between a liquid and a solid. [Synonym:Wetting Agent] (TR45) (TR26)
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Surrogate Fluid
A model process fluid used in a small-scale validation study. The fluid is intended to either match or resemble an actual process fluid as closely as is feasible. (TR41)
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Survivor Curve
Graphical representation of the inactivation of a population of microorganisms with increasing exposure to a microbicidal agent under stated conditions. (TR01) (TR3) (TR51) (TR61)