Glossary Terms (Simple List)
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Load Monitor
A chemical, physical or biological indicator that provides an indication that a load was exposed to moist heat processing conditions. Note: In the United States, the load monitor must consist of a device in the form of a chemical, physical or biological indicator that is capable of direct measurement, or if appropriate, an indirect measurement of physical lethality delivered to the load. (TR30)
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Load Zone
Area within the sterilization chamber where materials to be sterilized may be placed. (TR01) (TR3) (TR48)
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Loft
Thickness of an air-filled insulation material. (TR72)
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Log Partition or Partition Coefficient
The partition coefficient is a ratio of concentrations of un-ionized compound between the two solutions usually water and octanol. To measure the partition coefficient of ionizable solutes, the pH of the aqueous phase is adjusted such that the predominant form of the compound is un-ionized. The logarithm of the ratio of the concentration of the un-ionized solute in the solvents is called log P; The log P values is also known as a measure of lipophilicity. (TR55)
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Log Reduction
Log reduction is defined as the first log being 90%, the second log being 9% and the third log being 0.09% of the original inoculums. (TR70)
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Log Reduction Value (LRV)
The logarithm to the base 10 of the ratio of organisms in the feed to organisms in the filtrate. (i.e., Log10(109/2) = 9.7). [Synonym: Log Titer Reduction] (TR45)
Titer Reduction (TR) expressed as a base 10 logarithm. (TR75)
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Log Titer Reduction (LTR) or Log Reduction Value (LRV)
The virus reduction factor of an individual purification or inactivation step is defined as the log10 of the ratio of the virus titer or total load in the prepurification material and the virus titer or load in the post-purification material which is ready for use in the next step of the process. (TR41)
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Logistics Service Providers (ISP or 3PIs)
Freight forwarders and brokers that assist in moving the product, but may not physically touch the product. (TR52)
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Looped Memory
An electronic system with limited storage capacity that overwrites older data when it reaches that capacity. (TR84)
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Lost Work Day (LWD)
A day on which an employee does not work because of injury in a work-related accident. (TR52)